Concussion (child)

A Study to Investigate Mechanisms, Predictors, and Prevention of Persistent Post-Traumatic Headache

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Study type

Interventional

About this study

The purpose of this study is to identify mechanisms and predictors for the persistence of post-traumatic headache and methods to treat post-traumatic headache and prevent its persistence.  

Assessment of Traumatic Brain Injury with Multiparametric Magnetic Resonance Elastography

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About this study

The purpose of this study is to determine if there are changes in mild traumatic brain injury (mTBI) and/or repetitive head impacts (RHI) detectible with multiparametric MR Elastography (MRE). The hypothesis is that multiparametric MR Elastography will detect changes in the mechanical properties of human head tissues in patients following head traumas.  

A Study Evaluating the Use of 31P MRS to Assess Brain NAD+ Levels as Compared to Nicotinamide Riboside Supplementation in Healthy Current and Former Collegiate Athletes

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Study type

Interventional

About this study

The purpose of this study is to determine if nicotinamide riboside (750 mg/day for 12 weeks) can affect the levels of NAD+ in the brain as measured by 31P MRS.

A Study Evaluating the Use of 31P MRS to Assess Brain NAD+ Levels as Compared to Nicotinamide Riboside Supplementation in Healthy Current and Former Collegiate Athletes

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Study type

Interventional

About this study

The purpose of this study is to determine if nicotinamide riboside (750 mg/day for 12 weeks) can affect the levels of NAD+ in the brain as measured by 31P MRS.

A Study of Factors That Predispose, Promote, and Perpetuate Post-Traumatic Dizziness

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Study type

Observational

About this study

The purpose of this study is to investigate whether recent, groundbreaking discoveries about key pathophysiologic processes that drive chronic dizziness in patients without traumatic brain injury (TBI9,10) are applicable to patients with post-mTBI vestibular disability. We expect the results of this project to have practical clinical and research applications, providing novel data for two future steps:

Neurocognitive Dysfunction after Anesthesia in Patients with Recent Concussion

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Study type

Observational

About this study

The purpose of this study is to determine if anesthesia after concussion is associated with cognitive dysfunction, and if recent concussion is a patient safety risk in the perioperative period

Non-invasive Diagnostic for Assessing Elevated Intracranial Pressure

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Study type

Observational

About this study

The study is a prospective, multi-center, non-randomized, open label observational study. The objective of this study is to compare the accuracy of the EyeBOX to a clinical diagnosis of abnormal ICP as determined by an external ventriculostomy drain (EVD) or ventriculostomy catheter.

A Study to Test Concussion Return to Baseline after Elective Craniotomy Procedure

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Study type

Observational

About this study

The purpose of this study is to determine return to baseline (RTB) period after an elective craniotomy procedure using the ImPACT testing assessment.